Innate immunity and HBV persistence.
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ABSTRACT:
SUBMITTER: Chiale C
PROVIDER: S-EPMC8319108 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Publications
Innate immunity and HBV persistence.
Chiale Carolina C Marchese Anthony M AM Robek Michael D MD
Current opinion in virology 20210513
Hepatitis B virus (HBV) causes chronic infections that are associated with immune dysfunction. Though T cell impairment is perhaps the most prominent immune change contributing to viral persistence, HBV interaction with the innate immune system is also likely key, as the lack of effective innate immunity has functional consequences that promote chronic infection. In addition to an intrinsic ability to fight viral infections, the innate immune system also impacts T cell responses and other adapti ...[more]
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