Tertiary cytoreduction for recurrent ovarian carcinoma: An updated and expanded analysis.

ABSTRACT:

Objective

We sought to describe clinicopathologic and surgical factors associated with oncologic outcomes in patients undergoing tertiary cytoreduction and to present a clinical model to identify patients with high-grade serous ovarian cancer (HGSOC) who may benefit most from tertiary cytoreduction.

Methods

We retrospectively identified patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who underwent tertiary cytoreduction at our institution from 1/1/1990-1/1/2019. Kaplan-Meier curves were used to estimate survival and compared using the log-rank test. Cox-proportional hazards regression was used to detect variables associated with survival.

Results

Of 114 patients who met inclusion criteria, 79 (69.2%) had high-grade serous tumor

SUBMITTER: Manning-Geist BL 

PROVIDER: S-EPMC8319116 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature