An umbrella review of the evidence associating diet and cancer risk at 11 anatomical sites.

ABSTRACT: There is evidence that diet and nutrition are modifiable risk factors for several cancers, but associations may be flawed due to inherent biases. Nutritional epidemiology studies have largely relied on a single assessment of diet using food frequency questionnaires. We conduct an umbrella review of meta-analyses of observational studies to evaluate the strength and validity of the evidence for the association between food/nutrient intake and risk of developing or dying from 11 primary cancers. It is estimated that only few single food/nutrient and cancer associations are supported by strong or highly suggestive meta-analytic evidence, and future similar research is unlikely to change this evidence. Alcohol consumption is positively associated with risk of postmenopausal breast, colorectal,

SUBMITTER: Papadimitriou N 

PROVIDER: S-EPMC8319326 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature