Association between the use of balanced fluids and outcomes in critically ill children: a before and after study.

ABSTRACT:

Background

Hyperchloremia and chloride load have been associated with worse clinical outcomes in critically ill patients. We sought to evaluate the electrolyte profile and clinical outcomes associated with a unit-wide transition from saline to balanced fluids for resuscitation and maintenance fluids in a pediatric intensive care unit (PICU).

Methods

A before and after analysis of all patients admitted to the PICU in a large, urban, academic hospital between August 2018 and March 2020. The transition from the use of saline to the use of balanced fluids for both resuscitation and maintenance fluid as standard care occurred in June 2019. The primary outcome was day 3 acute kidney injury (AKI). The secondary outcomes included mortality, ventilator-free days (VFDs), need for rena

SUBMITTER: Barhight MF 

PROVIDER: S-EPMC8319885 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature