Osmium Arene Germyl, Stannyl, Germanate, and Stannate Complexes as Anticancer Agents.

ABSTRACT: Herein, we describe the synthesis, full spectroscopic characterization, DFT (density functional theory) calculations, and single-crystal X-ray diffraction analyses of a series of osmium arene σ-germyl, germanate, σ-stannyl, and stannate complexes, along with their cytotoxic (anticancer) investigations. The known dimer complexes [OsCl₂(η⁶-C₆H₆)]₂ (1) and [OsCl₂(η⁶-p-cymene)]₂ (2) were reacted with PPh₃ to form the known mononuclear complex [OsCl₂(η⁶-p-cymene)(PPh₃)] (3) and the new complex [OsCl₂(η⁶-C₆H₆)(PPh₃)] (6); complex 3 was reacted with GeCl₂

SUBMITTER: Nabiyeva T 

PROVIDER: S-EPMC8320079 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature