Association of pelvic inflammatory disease (PID) with ovarian cancer: a nationwide population-based retrospective cohort study from Taiwan.

ABSTRACT:

Background

Pelvic inflammatory disease (PID) is an important health issue for women. Infection and inflammation play an important role in carcinogenesis and PID has been reported to be associated with ovarian cancer in some small scale studies.

Aim

We sought to determine whether PID is associated with an elevated risk of ovarian cancer in Asian women.

Methods

Using data from Taiwan's National Health Insurance Research Database (NHIRD), our retrospective cohort study included women diagnosed with PID (cases) between the years of 2000 till 2012. Each case was matched with two women without PID (controls) by age and the year of first entry into the database. Both study cohorts were followed-up until the first event of ovarian cancer, withdrawal from the NHI program, deat

SUBMITTER: Chang CY 

PROVIDER: S-EPMC8320223 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature