Online Solid-Phase Extraction-Inductively Coupled Plasma-Quadrupole Mass Spectrometry with Oxygen Dynamic Reaction for Quantification of Technetium-99.

ABSTRACT: Quantification of pg/L levels (i.e., 0.6 mBq/L) of radioactive technetium-99 (⁹⁹Tc) was achieved within 15 min in the presence of isobaric and polyatomic interference sources such as ruthenium-99 (⁹⁹Ru) and molybdenum hydride (⁹⁸Mo¹H) at 3-11 orders of magnitude higher concentrations. Online solid-phase extraction-inductively coupled plasma-quadrupole mass spectrometry (ICP-QMS) with oxygen (O₂) dynamic reaction cell (online SPE-ICP-MS-DRC) was shown to be a thorough automatic analytical system, circumventing the need for human handling. At three stepwise separations (SPE-DRC-Q mass filters), we showed that interference materials allowed the coexistence of abundance ratios of 1.5 × 10^-13 and 1.1 × 10^-5 for ⁹⁹

SUBMITTER: Matsueda M 

PROVIDER: S-EPMC8320326 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature