Cardiac biomarkers and COVID-19: A systematic review and meta-analysis.

ABSTRACT:

Objective

To systematically investigate the relationship between cardiac biomarkers and COVID-19 severity and mortality.

Methods

We performed a literature search using PubMed, Web of Science, and Google Scholar. The standardized mean difference (SMD) and 95% confidence interval (CI) were applied to estimate the combined results of 67 studies. A meta-analysis of cardiac biomarkers was used to evaluate disease mortality and severity in COVID-19 patients.

Results

A meta-analysis of 7812 patients revealed that patients with high levels of cardiac troponin I (SMD = 0.81 U/L, 95% CI = 0.14-1.48, P = 0.017), cardiac troponin T (SMD = 0.78 U/L, 95% CI = 0.07-1.49, P = 0.032), high-sensitive cardiac troponin I (SMD = 0.66 pg/mL, 95% CI = 0.51-0.81, P < 0.001), high-sensitive c

SUBMITTER: An W 

PROVIDER: S-EPMC8320426 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature