The impact of continuous positive airway pressure treatment on retinal vascular changes in obstructive sleep apnea.

ABSTRACT:

Study objectives

Obstructive sleep apnea (OSA) was recently shown to be associated with quantifiable retinal vascular changes, which correlate with disease severity. This follow-up study examines the response of retinal vascular changes in patients with OSA receiving continuous positive airway pressure (CPAP) treatment.

Methods

This prospective cohort study recruited adult patients undergoing diagnostic polysomnography at a tertiary sleep clinic in Sydney, Australia, stratified into 4 groups by the apnea-hypopnea index; control patients and patients with mild, moderate, and severe OSA. At baseline and follow-up approximately 24 months later, static retinal vascular calibers were derived from fundus photographs, and dynamic vascular pulsation amplitudes were measured on video

SUBMITTER: Wong B 

PROVIDER: S-EPMC8320478 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature