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Knuckle cracking at night associated with sodium oxybate treatment.


ABSTRACT:

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During upward titration of a dose of sodium oxybate therapy for narcolepsy with cataplexy, a 25-year-old woman was observed by her husband to have new onset of knuckle-cracking and moaning behaviors during sleep ≥1 nights each week. The patient did previously occasionally crack her knuckles during the day (but never at night). These behaviors had not been evaluated by polysomnography. After transition of care, polysomnography with video monitoring was ordered and revealed 2 knuckle-cracking episodes that developed out of stage N2 sleep and were likely a non-rapid eye movement sleep parasomnia associated with sodium oxybate treatment.

SUBMITTER: Carbajal-Mamani S 

PROVIDER: S-EPMC8320495 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature

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Knuckle cracking at night associated with sodium oxybate treatment.

Carbajal-Mamani Semiramis S   Berry Richard B RB   Al Hourani Lubna L   Khatri Abhishek A   Ryals Scott S   Wagner Mary H MH  

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20210501 5


<h4>None</h4>During upward titration of a dose of sodium oxybate therapy for narcolepsy with cataplexy, a 25-year-old woman was observed by her husband to have new onset of knuckle-cracking and moaning behaviors during sleep ≥1 nights each week. The patient did previously occasionally crack her knuckles during the day (but never at night). These behaviors had not been evaluated by polysomnography. After transition of care, polysomnography with video monitoring was ordered and revealed 2 knuckle-  ...[more]

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