The seasonal pattern of restless legs syndrome in a sample from the Korean Health Insurance Review and Assessment Service national database.

ABSTRACT:

Study objectives

To assess the seasonality of restless legs syndrome (RLS) using data from the Korean national health insurance database.

Methods

We retrospectively reviewed a randomly selected sample representing 3% of the national health insurance claims database in South Korea. From this sample, we obtained the monthly numbers of patients with RLS and diagnoses from 2009 to 2016, along with prescriptions for monthly dopamine agonists and clonazepam for patients with RLS from 2009 to 2013. Total dopamine agonist and clonazepam doses were converted to levodopa-equivalent doses, and the monthly cumulative prescription dose was calculated. Cosinor analysis was used to evaluate the seasonal pattern of each variable.

Results

This study included 11,466 patients with RLS a

SUBMITTER: Oh SM 

PROVIDER: S-EPMC8320502 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature