Antigenic Diversity in <i>Theileria parva</i> Populations From Sympatric Cattle and African Buffalo Analyzed Using Long Read Sequencing.

ABSTRACT: East Coast fever (ECF) in cattle is caused by the Apicomplexan protozoan parasite Theileria parva, transmitted by the three-host tick Rhipicephalus appendiculatus. The African buffalo (Syncerus caffer) is the natural host for T. parva but does not suffer disease, whereas ECF is often fatal in cattle. The genetic relationship between T. parva populations circulating in cattle and buffalo is poorly understood, and has not been studied in sympatric buffalo and cattle. This study aimed to determine the genetic diversity of T. parva populations in cattle and buffalo, in an area where livestock co-exist with buffalo adjacent to the Serengeti National Park, Tanzania. Three T. parva antigens (Tp1, Tp4, and Tp16), known to be recognized by CD8^+<

SUBMITTER: Allan FK 

PROVIDER: S-EPMC8320539 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature