Differences in immune status and fecal SCFA between Indonesian stunted children and children with normal nutritional status.

ABSTRACT: We recently showed that the gut microbiota composition of stunted children was different from that of children with normal nutritional status. Here, we compared immune status and fecal microbial metabolite concentrations between stunted and normal children, and we correlated macronutrient intake (including energy), metabolites and immune status to microbiota composition. The results show that macronutrient intake was lower in stunted children for all components, but after correction for multiple comparison significant only for energy and fat. Only TGF-β was significantly different between stunted children and children of normal nutritional status after correction for multiple comparisons. TNF-alpha, IL-10, lipopolysaccharide binding protein in serum and secretory IgA in feces were not sign

SUBMITTER: Surono IS 

PROVIDER: S-EPMC8320972 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature