Efficacy and tolerability of exclusive enteral nutrition in adult patients with complicated Crohn's disease.

ABSTRACT:

Background/aims

Exclusive enteral nutrition (EEN), an established modality for pediatric Crohn's disease (CD) is seldomly utilized in adults. The present study reports the outcome of EEN in adult CD patients at a tertiary care hospital in India.

Methods

This was a retrospective analysis of CD patients who received EEN as a sole modality/adjunct to other treatment. The primary and secondary outcomes changed in Crohn's Disease Activity Index (CDAI), and clinical response (decline in CDAI > 70), respectively, at 4 and 8 weeks. Subgroup analysis evaluated response across different phenotypes, EEN formulations and prior treatment. Linear mixed effect model was created to assess the predictors of EEN response.

Results

Thirty-one CD patients received EEN over median duration

SUBMITTER: Sharma S 

PROVIDER: S-EPMC8322023 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature