Resting state functional networks in 1-to-3-year-old typically developing children.

ABSTRACT: Brain functional networks undergo substantial development and refinement during the first years of life. Yet, the maturational pathways of functional network development remain poorly understood. Using resting-state fMRI data acquired during natural sleep from 24 typically developing toddlers, ages 1.5-3.5 years, we aimed to examine the large-scale resting-state functional networks and their relationship with age and developmental skills. Specifically, two network organization indices reflecting network connectivity and spatial variability were derived. Our results revealed that reduced spatial variability or increased network homogeneity in one of the default mode network components was associated with age, with older children displaying less spatially variable posterior DMN subcomponent,

SUBMITTER: Chen B 

PROVIDER: S-EPMC8322300 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature