National systemic lupus erythematosus prospective cohort in Saudi Arabia: A study protocol.

ABSTRACT:

Abstract

Systemic Lupus erythematosus (SLE) is a chronic multisystem, multifactorial inflammatory autoimmune disease. The SLE patients have 3 times increased risk of mortality based on international data with ethnicity playing an important impact on patients' morbidity and mortality. Descriptive studies from Saudi Arabia showed variation in clinical features from one region to another. Moreover, reliable inference from these studies is limited by study methodology and lack of translational data using biological samples to understand clinical phenotypes of Saudi SLE patients.The aim of this report is to describe the prospective study protocol of the National Systemic Lupus Erythematosus Cohort in Saudi Arabia. The purpose of this cohort study is multifold: first, to examine clinical

SUBMITTER: Almaghlouth IA 

PROVIDER: S-EPMC8322486 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature