Performance of Ga-68 PSMA PET/CT for diagnosis and grading of local prostate cancer.

ABSTRACT:

Background

We aimed to evaluate the utility of prostate-specific membrane antigen (PSMA) PET/CT for the detection of local disease within the prostate.

Methods

This is a retrospective review of a single-center experience evaluating intraprostatic detection rates compared with final histopathology in a radical prostatectomy (RP) population. Seventy-two patients had PSMA PET/CT scan performed as part of their primary staging. Intraprostatic PSMA PET/CT avidity was assessed. PSMA PET/CT uptake was retrospectively correlated with patient characteristics including final histopathology, MRI Prostate Imaging Reporting and Data System (PI-RADS) score, clinical tumor stage, prostate-specific antigen (PSA) level, and patient age.

Results

The sensitivity of PSMA PET/CT for the d

SUBMITTER: Kwan TN 

PROVIDER: S-EPMC8322807 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature