Dataset Information

30-Day Morbidity and Mortality of Bariatric Surgery During the COVID-19 Pandemic: a Multinational Cohort Study of 7704 Patients from 42 Countries.

ABSTRACT:

Background

There are data on the safety of cancer surgery and the efficacy of preventive strategies on the prevention of postoperative symptomatic COVID-19 in these patients. But there is little such data for any elective surgery. The main objectives of this study were to examine the safety of bariatric surgery (BS) during the coronavirus disease 2019 (COVID-19) pandemic and to determine the efficacy of perioperative COVID-19 protective strategies on postoperative symptomatic COVID-19 rates.

Methods

We conducted an international cohort study to determine all-cause and COVID-19-specific 30-day morbidity and mortality of BS performed between 01/05/2020 and 31/10/2020.

Results

Four hundred ninety-nine surgeons from 185 centres in 42 countries provided data on 7704 patients. Elective primary BS (n = 7084) was associated with a 30-day morbidity of 6.76% (n = 479) and a 30-day mortality of 0.14% (n = 10). Emergency BS, revisional BS, insulin-treated type 2 diabetes, and untreated obstructive sleep apnoea were associated with increased complications on multivariable analysis. Forty-three patients developed symptomatic COVID-19 postoperatively, with a higher risk in non-whites. Preoperative self-isolation, preoperative testing for SARS-CoV-2, and surgery in institutions not concurrently treating COVID-19 patients did not reduce the incidence of postoperative COVID-19. Postoperative symptomatic COVID-19 was more likely if the surgery was performed during a COVID-19 peak in that country.

Conclusions

BS can be performed safely during the COVID-19 pandemic with appropriate perioperative protocols. There was no relationship between preoperative testing for COVID-19 and self-isolation with symptomatic postoperative COVID-19. The risk of postoperative COVID-19 risk was greater in non-whites or if BS was performed during a local peak.

SUBMITTER: Singhal R

PROVIDER: S-EPMC8323543 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature

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Publications

30-Day Morbidity and Mortality of Bariatric Surgery During the COVID-19 Pandemic: a Multinational Cohort Study of 7704 Patients from 42 Countries.

Singhal Rishi R Ludwig Christian C Rudge Gavin G Gkoutos Georgios V GV Tahrani Abd A Mahawar Kamal K Pędziwiatr Michał M Major Piotr P Zarzycki Piotr P Pantelis Athanasios A Lapatsanis Dimitris P DP Stravodimos Georgios G Matthys Chris C Focquet Marc M Vleeschouwers Wouter W Spaventa Antonio G AG Zerrweck Carlos C Vitiello Antonio A Berardi Giovanna G Musella Mario M Sanchez-Meza Alberto A Cantu Felipe J FJ Mora Fernando F Cantu Marco A MA Katakwar Abhishek A Reddy D Nageshwar DN Elmaleh Haitham H Hassan Mohammad M Elghandour Abdelrahman A Elbanna Mohey M Osman Ahmed A Khan Athar A Layani Laurent L Kiran Nalini N Velikorechin Andrey A Solovyeva Maria M Melali Hamid H Shahabi Shahab S Agrawal Ashish A Shrivastava Apoorv A Sharma Ankur A Narwaria Bhavya B Narwaria Mahendra M Raziel Asnat A Sakran Nasser N Susmallian Sergio S Karagöz Levent L Akbaba Murat M Pişkin Salih Zeki SZ Balta Ahmet Ziya AZ Senol Zafer Z Manno Emilio E Iovino Michele Giuseppe MG Osman Ahmed A Qassem Mohamed M Arana-Garza Sebastián S Povoas Heitor P HP Vilas-Boas Marcos Leão ML Naumann David D Super Jonathan J Li Alan A Ammori Basil J BJ Balamoun Hany H Salman Mohammed M Nasta Amrit Manik AM Goel Ramen R Sánchez-Aguilar Hugo H Herrera Miguel F MF Abou-Mrad Adel A Cloix Lucie L Mazzini Guilherme Silva GS Kristem Leonardo L Lazaro Andre A Campos Jose J Bernardo Joaquín J González Jesús J Trindade Carlos C Viveiros Octávio O Ribeiro Rui R Goitein David D Hazzan David D Segev Lior L Beck Tamar T Reyes Hernán H Monterrubio Jerónimo J García Paulina P Benois Marine M Kassir Radwan R Contine Alessandro A Elshafei Moustafa M Aktas Sueleyman S Weiner Sylvia S Heidsieck Till T Level Luis L Pinango Silvia S Ortega Patricia Martinez PM Moncada Rafael R Valenti Victor V Vlahović Ivan I Boras Zdenko Z Liagre Arnaud A Martini Francesco F Juglard Gildas G Motwani Manish M Saggu Sukhvinder Singh SS Al Moman Hazem H López Luis Adolfo Aceves LAA Cortez María Angelina Contreras MAC Zavala Rodrigo Aceves RA D'Haese Christine C Kempeneers Ivo I Himpens Jacques J Lazzati Andrea A Paolino Luca L Bathaei Sarah S Bedirli Abdulkadir A Yavuz Aydın A Büyükkasap Çağrı Ç Özaydın Safa S Kwiatkowski Andrzej A Bartosiak Katarzyna K Walędziak Maciej M Santonicola Antonella A Angrisani Luigi L Iovino Paola P Palma Rossella R Iossa Angelo A Boru Cristian Eugeniu CE De Angelis Francesco F Silecchia Gianfranco G Hussain Abdulzahra A Balchandra Srivinasan S Coltell Izaskun Balciscueta IB Pérez Javier Lorenzo JL Bohra Ashok A Awan Altaf K AK Madhok Brijesh B Leeder Paul C PC Awad Sherif S Al-Khyatt Waleed W Shoma Ashraf A Elghadban Hosam H Ghareeb Sameh S Mathews Bryan B Kurian Marina M Larentzakis Andreas A Vrakopoulou Gavriella Zoi GZ Albanopoulos Konstantinos K Bozdag Ahemt A Lale Azmi A Kirkil Cuneyt C Dincer Mursid M Bashir Ahmad A Haddad Ashraf A Hijleh Leen Abu LA Zilberstein Bruno B de Marchi Danilo Dallago DD Souza Willy Petrini WP Brodén Carl Magnus CM Gislason Hjörtur H Shah Kamran K Ambrosi Antonio A Pavone Giovanna G Tartaglia Nicola N Kona S Lakshmi Kumari SLK Kalyan K K Perez Cesar Ernesto Guevara CEG Botero Miguel Alberto Forero MAF Covic Adrian A Timofte Daniel D Maxim Madalina M Faraj Dashti D Tseng Larissa L Liem Ronald R Ören Gürdal G Dilektasli Evren E Yalcin Ilker I AlMukhtar Hudhaifa H Al Hadad Mohammed M Mohan Rasmi R Arora Naresh N Bedi Digvijaysingh D Rives-Lange Claire C Chevallier Jean-Marc JM Poghosyan Tigran T Sebbag Hugues H Zinaï Lamia L Khaldi Saadi S Mauchien Charles C Mazza Davide D Dinescu Georgiana G Rea Bernardo B Pérez-Galaz Fernando F Zavala Luis L Besa Anais A Curell Anna A Balibrea Jose M JM Vaz Carlos C Galindo Luis L Silva Nelson N Caballero José Luis Estrada JLE Sebastian Sergio Ortiz SO Marchesini João Caetano Dallegrave JCD da Fonseca Pereira Ricardo Arcanjo RA Sobottka Wagner Herbert WH Fiolo Felipe Eduardo FE Turchi Matias M Coelho Antonio Claudio Jamel ACJ Zacaron Andre Luis AL Barbosa André A Quinino Reynaldo R Menaldi Gabriel G Paleari Nicolás N Martinez-Duartez Pedro P de Aragon Ramírez de Esparza Gabriel Martínez GM Esteban Valentin Sierra VS Torres Antonio A Garcia-Galocha Jose Luis JL Josa Miguel M Pacheco-Garcia Jose Manuel JM Mayo-Ossorio Maria Angeles MA Chowbey Pradeep P Soni Vandana V de Vasconcelos Cunha Hercio Azevedo HA Castilho Michel Victor MV Ferreira Rafael Meneguzzi Alves RMA Barreiro Thiago Alvim TA Charalabopoulos Alexandros A Sdralis Elias E Davakis Spyridon S Bomans Benoit B Dapri Giovanni G Van Belle Koenraad K Takieddine Mazen M Vaneukem Pol P Karaca Esma Seda Akalın ESA Karaca Fatih Can FC Sumer Aziz A Peksen Caghan C Savas Osman Anil OA Chousleb Elias E Elmokayed Fahad F Fakhereldin Islam I Aboshanab Hany Mohamed HM Swelium Talal T Gudal Ahmad A Gamloo Lamees L Ugale Ayushka A Ugale Surendra S Boeker Clara C Reetz Christian C Hakami Ibrahim Ali IA Mall Julian J Alexandrou Andreas A Baili Efstratia E Bodnar Zsolt Z Maleckas Almantas A Gudaityte Rita R Guldogan Cem Emir CE Gundogdu Emre E Ozmen Mehmet Mahir MM Thakkar Deepti D Dukkipati Nandakishore N Shah Poonam Shashank PS Shah Shashank Subhashchandra SS Shah Simran Shashank SS Adil Md Tanveer MT Jambulingam Periyathambi P Mamidanna Ravikrishna R Whitelaw Douglas D Adil Md Tanveer MT Jain Vigyan V Veetil Deepa Kizhakke DK Wadhawan Randeep R Torres Antonio A Torres Max M Tinoco Tabata T Leclercq Wouter W Romeijn Marleen M van de Pas Kelly K Alkhazraji Ali K AK Taha Safwan A SA Ustun Murat M Yigit Taner T Inam Aatif A Burhanulhaq Muhammad M Pazouki Abdolreza A Eghbali Foolad F Kermansaravi Mohammad M Jazi Amir Hosein Davarpanah AHD Mahmoudieh Mohsen M Mogharehabed Neda N Tsiotos Gregory G Stamou Konstantinos K Barrera Rodriguez Francisco J FJ Rojas Navarro Marco A MA Torres Omar MOhamed OM Martinez Sergio Lopez SL Tamez Elda Rocio Maltos ERM Millan Cornejo Gustavo A GA Flores Jose Eduardo Garcia JEG Mohammed Diya Aldeen DA Elfawal Mohamad Hayssam MH Shabbir Asim A Guowei Kim K So Jimmy By JB Kaplan Elif Tuğçe ET Kaplan Mehmet M Kaplan Tuğba T Pham DangTuan D Rana Gurteshwar G Kappus Mojdeh M Gadani Riddish R Kahitan Manish M Pokharel Koshish K Osborne Alan A Pournaras Dimitri D Hewes James J Napolitano Errichetta E Chiappetta Sonja S Bottino Vincenzo V Dorado Evelyn E Schoettler Axel A Gaertner Daniel D Fedtke Katharina K Aguilar-Espinosa Francisco F Aceves-Lozano Saul S Balani Alessandro A Nagliati Carlo C Pennisi Damiano D Rizzi Andrea A Frattini Francesco F Foschi Diego D Benuzzi Laura L Parikh Chirag C Shah Harshil H Pinotti Enrico E Montuori Mauro M Borrelli Vincenzo V Dargent Jerome J Copaescu Catalin A CA Hutopila Ionut I Smeu Bogdan B Witteman Bart B Hazebroek Eric E Deden Laura L Heusschen Laura L Okkema Sietske S Aufenacker Theo T den Hengst Willem W Vening Wouter W van der Burgh Yonta Y Ghazal Ahmad A Ibrahim Hamza H Niazi Mourad M Alkhaffaf Bilal B Altarawni Mohammad M Cesana Giovanni Carlo GC Anselmino Marco M Uccelli Matteo M Olmi Stefano S Stier Christine C Akmanlar Tahsin T Sonnenberg Thomas T Schieferbein Uwe U Marcolini Alejandro A Awruch Diego D Vicentin Marco M de Souza Bastos Eduardo Lemos EL Gregorio Samuel Azenha SA Ahuja Anmol A Mittal Tarun T Bolckmans Roel R Wiggins Tom T Baratte Clément C Wisnewsky Judith Aron JA Genser Laurent L Chong Lynn L Taylor Lillian L Ward Salena S Chong Lynn L Taylor Lillian L Hi Michael W MW Heneghan Helen H Fearon Naomi N Plamper Andreas A Rheinwalt Karl K Heneghan Helen H Geoghegan Justin J Ng Kin Cheung KC Fearon Naomi N Kaseja Krzysztof K Kotowski Maciej M Samarkandy Tarig A TA Leyva-Alvizo Adolfo A Corzo-Culebro Lourdes L Wang Cunchuan C Yang Wah W Dong Zhiyong Z Riera Manel M Jain Rajesh R Hamed Hosam H Said Mohammed M Zarzar Katia K Garcia Manuel M Türkçapar Ahmet Gökhan AG Şen Ozan O Baldini Edoardo E Conti Luigi L Wietzycoski Cacio C Lopes Eduardo E Pintar Tadeja T Salobir Jure J Aydin Cengiz C Atici Semra Demirli SD Ergin Anıl A Ciyiltepe Huseyin H Bozkurt Mehmet Abdussamet MA Kizilkaya Mehmet Celal MC Onalan Nezihe Berrin Dodur NBD Zuber Mariana Nabila Binti Ahmad MNBA Wong Wei Jin WJ Garcia Amador A Vidal Laura L Beisani Marc M Pasquier Jorge J Vilallonga Ramon R Sharma Sharad S Parmar Chetan C Lee Lyndcie L Sufi Pratik P Sinan Hüseyin H Saydam Mehmet M

Obesity surgery 20210730 10

<h4>Background</h4>There are data on the safety of cancer surgery and the efficacy of preventive strategies on the prevention of postoperative symptomatic COVID-19 in these patients. But there is little such data for any elective surgery. The main objectives of this study were to examine the safety of bariatric surgery (BS) during the coronavirus disease 2019 (COVID-19) pandemic and to determine the efficacy of perioperative COVID-19 protective strategies on postoperative symptomatic COVID-19 ra ...[more]

PMID: 34328624

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Project description:PurposeThe 30-day mortality rate after hip fracture surgery has been considered as an indirect indicator of the quality of care. The aim of this work is to analyse preoperative and postoperative factors potentially related to early 30-day mortality in patients over 65 undergoing hip fracture surgery.MethodsProspective cohort study including all consecutive primary hip fracture patients over 65 admitted to Trauma and Orthopaedics department from January 1, 2018 to December 31, 2019. Bed-ridden, non- surgically treated patients, and high energy trauma or tumoral aetiology fractures were excluded. A total of 943 patients were eligible (attrition rate: 2.1%). Follow-up included 30-days after discharge. We noted the 30-day mortality after hip fracture surgery, analysing 130 potentially related variables including biodemographic, fracture-related, preoperative, and postoperative clinical factors. Qualitative variables were assessed by χ2, and quantitative variables by non-parametric tests. Odds ratio determined by binary logistic regression. We selected preventable candidate variables for multivariate risk assessment by logistic regression.ResultsA total of 923 patients were enrolled (mean age 86.22±6.8, 72.9% women). The 30-day mortality rate was 6.0%. We noted significant increased mortality on men (OR = 2.381[1.371-4.136], p = 0.002), ageing patients (ORyear = 1.073[1.025-1.122], p = 0.002), and longer time to surgery (ORday = 1.183[1.039-1146], p<0.001), on other 20 preoperative clinical variables, like lymphopenia (lymphocyte count <103/μl, OR = 1.842[1.063-3.191], p = 0.029), hypoalbuminemia (≤3.5g/dl, OR = 2.474[1.316-4.643], p = 0.005), and oral anticoagulant intake (OR = 2.499[1.415-4.415], p = 0.002), and on 25 postoperative clinical variables, like arrhythmia (OR = 13.937[6.263-31.017], p<0.001), respiratory insufficiency (OR = 7.002[3.947-12.419], p<0.001), hyperkalaemia (OR = 10.378[3.909-27.555], p<0.001), nutritional supply requirement (OR = 3.576[1.894-6.752], p = 0.021), or early arthroplasty dislocation (OR = 6.557[1.206-35.640], p = 0.029). We developed a predictive model for early mortality after hip fracture surgery based on postoperative factors with 96.0% sensitivity and 60.7% specificity (AUC = 0.863).ConclusionWe revealed that not only preoperative, but also postoperative factors have a great impact after hip fracture surgery. The influence of post-operative factors on 30-day mortality has a logical basis, albeit so far they have not been identified or quantified before. Our results provide an advantageous picture of the 30-day mortality after hip fracture surgery.

Project description:BackgroundPostoperative mortality after colorectal cancer surgery varies across hospitals and countries. The aim of this study was to test the Association of Coloproctologists of Great Britain and Ireland (ACPGBI) models as predictors of 30-day mortality in an Australian cohort.MethodsData from patients who underwent surgery in six hospitals between 1996 and 2015 (CRC data set) were reviewed to test ACPGBI models, and patients from 79 hospitals in the Bi-National Colorectal Cancer Audit between 2007 and 2016 (BCCA data set) were analysed to validate model performance. Recalibrated models based on ACPGBI risk models were developed, tested and validated on a data set of Australasian patients.ResultsOf 18 752 patients observed during the study, 6727 (CRC data set) and 3814 (BCCA data set) were analysed. The 30-day mortality rate was 1·1 and 3·5 per cent in the CRC and BCCA data sets respectively. Both the original and revised ACPGBI models overestimated 30-day mortality for the CRC data set (observed to expected (O/E) ratio 0·17 and 0·21 respectively). Their ability to correctly predict mortality risk was poor (P < 0·001, Hosmer-Lemeshow test); however, the area under the curve for both models was 0·88 (95 per cent c.i. 0·85 to 0·92) showing good discriminatory power to classify 30-day mortality. The recalibrated original model performed well for calibration and discrimination, whereas the recalibrated revised model performed well for discrimination but not for calibration. Risk prediction was good for both recalibrated models. On external validation using the BCCA data set, the recalibrated models underestimated mortality risk (O/E ratio 3·06 and 2·98 respectively), whereas both original and revised ACPGBI models overestimated the risk (O/E ratio 0·48 and 0·69). All models showed similar good discrimination.ConclusionThe original and revised ACPGBI models overpredicted risk of 30-day mortality. The new Australasian calibrated ACPGBI model needs to be tested further in clinical practice.

Dataset Information

30-Day Morbidity and Mortality of Bariatric Surgery During the COVID-19 Pandemic: a Multinational Cohort Study of 7704 Patients from 42 Countries.

Background

Methods

Results

Conclusions

Publications

30-Day Morbidity and Mortality of Bariatric Surgery During the COVID-19 Pandemic: a Multinational Cohort Study of 7704 Patients from 42 Countries.

Similar Datasets

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