Human adenovirus species in children with acute respiratory illnesses.

ABSTRACT:

Background

Human adenovirus (HAdV) species B, C, and E are commonly associated with acute respiratory illnesses (ARI). We sought to determine the association between HAdV species and ARI severity in children over one respiratory season at Monroe Carell Jr. Children's Hospital at Vanderbilt.

Methods

We conducted a retrospective cohort study of children with HAdV from a provider-ordered BioFire® FilmArray Respiratory Pathogen Panel 2.0 (RPP) from 05/2018-06/2019. Type-specific PCR assays for HAdV-B3, B7, B11, B14, B16, B21, HAdV-C1, C2, C5, C6, and HAdV-E4 were performed. Demographics, clinical characteristics, and outcome data were compared between HAdV species.

Results

Of 4514 respiratory specimens collected, 2644 (59 %) had at least one pathogen detected by RPP, and

SUBMITTER: Probst V 

PROVIDER: S-EPMC8324062 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature