Magnesium intake is associated with a reduced risk of incident liver cancer, based on an analysis of the NIH-American Association of Retired Persons (NIH-AARP) Diet and Health Study prospective cohort.

ABSTRACT:

Background

Liver cancer incidence and mortality are escalating globally. Magnesium intake has been studied extensively in nonmalignant liver pathology, but the association between dietary intake of magnesium and primary liver malignancy has not been previously evaluated.

Objectives

We aimed to determine the association between total magnesium intake and primary liver cancer risk.

Methods

Using the NIH-American Association of Retired Persons (NIH-AARP) Diet and Health Study prospective cohort, we estimated the association between magnesium intake and the risk of incident primary liver cancer using Cox proportional hazard modeling adjusted for relevant confounders. Comprehensive stratified and sensitivity analyses were performed.

Results

During 6.4 million person

SUBMITTER: Shah SC 

PROVIDER: S-EPMC8324220 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature