Quantitative Susceptibility Mapping of Venous Vessels in Neonates with Perinatal Asphyxia.

ABSTRACT:

Background and purpose

Cerebral venous oxygen saturation can be used as an indirect measure of brain health, yet it often requires either an invasive procedure or a noninvasive technique with poor sensitivity. We aimed to test whether cerebral venous oxygen saturation could be measured using quantitative susceptibility mapping, an MR imaging technique, in 3 distinct groups: healthy term neonates, injured term neonates, and preterm neonates.

Materials and methods

We acquired multiecho gradient-echo MR imaging data in 16 neonates with perinatal asphyxia and moderate or severe hypoxic-ischemic encephalopathy (8 term age: average, 40.0 [SD, 0.8]  weeks' gestational age; 8 preterm, 33.5 [SD, 2.0]  weeks' gestational age) and in 8 healthy term-age controls (39.3 [SD, 0.6] weeks, f

SUBMITTER: Weber AM 

PROVIDER: S-EPMC8324259 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature