Multiple neuronal networks coordinate Hydra mechanosensory behavior.

ABSTRACT: Hydra vulgaris is an emerging model organism for neuroscience due to its small size, transparency, genetic tractability, and regenerative nervous system; however, fundamental properties of its sensorimotor behaviors remain unknown. Here, we use microfluidic devices combined with fluorescent calcium imaging and surgical resectioning to study how the diffuse nervous system coordinates Hydra's mechanosensory response. Mechanical stimuli cause animals to contract, and we find this response relies on at least two distinct networks of neurons in the oral and aboral regions of the animal. Different activity patterns arise in these networks depending on whether the animal is contracting spontaneously or contracting in response to mechanical stimulation. Together, these findings impro

SUBMITTER: Badhiwala KN 

PROVIDER: S-EPMC8324302 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature