Optimization of SPECT/CT imaging protocols for quantitative and qualitative ^99mTc SPECT.

ABSTRACT:

Background

The introduction of hybrid SPECT/CT devices enables quantitative imaging in SPECT, providing a methodological setup for quantitation using SPECT tracers comparable to PET/CT. We evaluated a specific quantitative reconstruction algorithm for SPECT data using a ^99mTc-filled NEMA phantom. Quantitative and qualitative image parameters were evaluated for different parametrizations of the acquisition and reconstruction protocol to identify an optimized quantitative protocol.

Results

The reconstructed activity concentration (AC_rec) and the signal-to-noise ratio (SNR) of all examined protocols (n = 16) were significantly affected by the parametrization of the weighting factor k used in scatter correction, the total number of iterations and the sphere

SUBMITTER: Kupitz D 

PROVIDER: S-EPMC8324619 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature