Brivaracetam Retention Rate and Seizure Outcomes in Patients with Drug-Resistant Focal Epilepsy Included in the Medical Need Program in Belgium: A Real-World, Multicenter, Chart Review.

ABSTRACT:

Background

New treatments are needed for patients with drug-resistant epilepsy to improve seizure control without decreasing quality of life.

Objective

In Belgium, a Medical Need Program (MNP) was initiated to make a new antiepileptic drug (brivaracetam; high-affinity synaptic vesicle protein 2A ligand) available as adjunctive therapy to treat focal seizures in patients failing treatment with three or more different antiepileptic drugs. This is a real-world chart review of the majority of patients (71%) enrolled in the MNP.

Patients and methods

Retention and seizure outcomes of brivaracetam adjunctive treatment were evaluated in 175 patients aged ≥ 16 years enrolled in the MNP between June 2016 and May 2017 at six centers; 95.4% were previously/concomitantly treated w

SUBMITTER: Depondt C 

PROVIDER: S-EPMC8324749 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature