Investigating the performance of 24-h urinary sucrose and fructose as a biomarker of total sugars intake in US participants - a controlled feeding study.

ABSTRACT:

Background

Developing approaches for the objective assessment of sugars intake in population research is crucial for generating reliable disease risk estimates, and evidence-based dietary guidelines. Twenty-four-hour urinary sucrose and fructose (24uSF) was developed as a predictive biomarker of total sugars intake based on 3 UK feeding studies, yet its performance as a biomarker of total sugars among US participants is unknown.

Objectives

To investigate the performance of 24uSF as a biomarker of sugars intake among US participants, and to characterize its use.

Methods

Ninety-eight participants, aged 18-70 y, consumed their usual diet under controlled conditions of a feeding study for 15 d, and collected 8 nonconsecutive 24-h urines measured for sucrose and fructose.<

SUBMITTER: Tasevska N 

PROVIDER: S-EPMC8326031 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature