Diet and erythrocyte metal concentrations in early pregnancy-cross-sectional analysis in Project Viva.

ABSTRACT:

Background

Dietary sources of metals are not well established among pregnant women in the United States.

Objective

We aimed to perform a diet-wide association study (DWAS) of metals during the first trimester of pregnancy.

Methods

In early pregnancy (11.3 ± 2.8 weeks of gestation), 1196 women from Project Viva (recruited 1999-2002 in eastern Massachusetts) completed a validated FFQ (135 food items) and underwent measurements of erythrocyte metals [arsenic (As), barium, cadmium, cesium (Cs), copper, mercury (Hg), magnesium, manganese, lead (Pb), selenium (Se), zinc]. The DWAS involved a systematic evaluation and visualization of all bivariate relations for each food-metal combination. For dietary items with strong associations with erythrocyte metals, we applied target

SUBMITTER: Lin PD 

PROVIDER: S-EPMC8326032 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature