Associative Conditioning Is a Robust Systemic Behavior in Unicellular Organisms: An Interspecies Comparison.

ABSTRACT: The capacity to learn new efficient systemic behavior is a fundamental issue of contemporary biology. We have recently observed, in a preliminary analysis, the emergence of conditioned behavior in some individual amoebae cells. In these experiments, cells were able to acquire new migratory patterns and remember them for long periods of their cellular cycle, forgetting them later on. Here, following a similar conceptual framework of Pavlov's experiments, we have exhaustively studied the migration trajectories of more than 2000 individual cells belonging to three different species: Amoeba proteus, Metamoeba leningradensis, and Amoeba borokensis. Fundamentally, we have analyzed several relevant properties of conditioned cells, such as the intensity of the responses, the d

SUBMITTER: Carrasco-Pujante J 

PROVIDER: S-EPMC8327096 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature