On-line daily plan optimization combined with a virtual couch shift procedure to address intrafraction motion in prostate magnetic resonance guided radiotherapy.

ABSTRACT:

Background and purpose

In daily adaptive magnetic resonance (MR)-guided radiotherapy, plans are adapted based on the patient's daily anatomy. During this adaptation phase, prostate intrafraction motion (IM) can occur. The aim of this study was to investigate the efficacy of always applying a subsequent virtual couch shift (VCS) to counter IM that occurred during the daily contour and plan adaption (CPa) procedure.

Material and methods

One hundred fifty patients with low and intermediate risk prostate cancer were treated with 5x7.25 Gy fractions on a 1.5 T MR-Linac. In each fraction, contour adaptation and dose re-optimization was performed using the session's first MR-scan. IM that occurred here was countered using two methods. One patient group had selective VCS (sVCS) appl

SUBMITTER: de Muinck Keizer DM 

PROVIDER: S-EPMC8327343 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature