Autistic traits in psychotic disorders: prevalence, familial risk, and impact on social functioning.

ABSTRACT:

Background

Prevalence estimates of autistic traits in individuals with psychotic disorders (PD) vary greatly and it is unclear whether individuals with a familial risk (FR) for psychosis have an increased propensity to display autistic traits. Furthermore, it is unknown whether the presence of comorbid autism traits disproportionally affects the cognitive and behavioral aspects of social functioning in PD.

Methods

In total, 504 individuals with PD, 587 unaffected siblings with FR, and 337 typical comparison (TC) individuals (16-50 years) were included. Autistic and psychotic traits were measured with the Autism Spectrum Quotient (AQ) and the Community Assessment of Psychic Experiences (CAPE). Social cognition was assessed with the Picture Sequencing Task (PST) and social beh

SUBMITTER: Ziermans TB 

PROVIDER: S-EPMC8327624 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature