Cognitive function after electroconvulsive therapy for depression: relationship to clinical response.

ABSTRACT:

Background

As uncertainty remains about whether clinical response influences cognitive function after electroconvulsive therapy (ECT) for depression, we examined the effect of remission status on cognitive function in depressed patients 4 months after a course of ECT.

Method

A secondary analysis was undertaken on participants completing a randomised controlled trial of ketamine augmentation of ECT for depression who were categorised by remission status (MADRS ⩽10 v. >10) 4 months after ECT. Cognition was assessed with self-rated memory and neuropsychological tests of anterograde verbal and visual memory, autobiographical memory, verbal fluency and working memory. Patients were assessed through the study, healthy controls on a single occasion, and compared using analysis of v

SUBMITTER: Anderson IM 

PROVIDER: S-EPMC8327625 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature