Development and validation of tumor-to-blood based nomograms for preoperative prediction of lymph node metastasis in lung cancer.

ABSTRACT:

Background

To develop and validate tumor-to-blood based nomograms for preoperative prediction of lymph node (LN) metastasis in patients with lung cancer (LC).

Methods

A prediction model was developed in a primary cohort comprising 330 LN stations from patients with pathologically confirmed LC, these data having been gathered from January 2016 to June 2019. Tumor-to-blood variables of LNs were calculated from positron emission tomography-computed tomography (PET-CT) images of LC and the short axis diameters of LNs were measured on CT images. Tumor-to-blood variables, number of stations suspected of harboring LN metastasis according to PET, and independent clinicopathological risk factors were included in the final nomograms. After being internally validated, the nomograms wer

SUBMITTER: Fu Y 

PROVIDER: S-EPMC8327690 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature