Variation in estimated viral suppression associated with the definition of viral suppression used.

ABSTRACT:

Objective

The proportion of people living with HIV with suppressed viral load is a key indicator of the HIV care continuum. We explored how this proportion varied depending on how it was calculated.

Design

Observational cohort study.

Methods

We calculated the proportion of the Johns Hopkins HIV Clinical Cohort who were virally suppressed each year, 2010-2018, based on different denominators; thresholds for suppression (≤20, ≤50, ≤200, or ≤400 copies/ml); and strategies for summarizing multiple viral load measurements (we classified persons as suppressed if they had any lab, ≥50% of labs, last lab, or all labs below the threshold). We also calculated 5-year risk of all-cause mortality associated with each classification of viral suppression.

Results

Three thousa

SUBMITTER: Lesko CR 

PROVIDER: S-EPMC8327702 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature