Characteristics of immune and inflammatory responses among different age groups of pediatric patients with COVID-19 in China.

ABSTRACT:

Background

Severe cases of coronavirus disease 2019 (COVID-19) among pediatric patients are more common in children less than 1 year of age. Our aim is to address the underlying role of immunity and inflammation conditions among different age groups of pediatric patients.

Methods

We recruited pediatric patients confirmed of moderate COVID-19 symptoms, admitted to Wuhan Children's Hospital from January 28th to April 1st in 2020. Patients were divided into four age groups (≤ 1, 1-6, 7-10, and 11-15 years). Demographic information, clinical characteristics, laboratory results of lymphocyte subsets test, immune and inflammation related markers were all evaluated.

Results

Analysis included 217/241 (90.0%) of patients with moderate clinical stage disease. Average recovery t

SUBMITTER: Ji SQ 

PROVIDER: S-EPMC8328122 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature