Modulation of Working Memory and Resting-State fMRI by tDCS of the Right Frontoparietal Network.

ABSTRACT: Many cognitive functions, including working memory, are processed within large-scale brain networks. We targeted the right frontoparietal network (FPN) with one session of transcranial direct current stimulation (tDCS) in an attempt to modulate the cognitive speed of a visual working memory task (WMT) in 27 young healthy subjects using a double-blind crossover design. We further explored the neural underpinnings of induced changes by performing resting-state fMRI prior to and immediately after each stimulation session with the main focus on the interaction between a task-positive FPN and a task-negative default mode network (DMN). Twenty minutes of 2 mA anodal tDCS was superior to sham stimulation in terms of cognitive speed manipulation of a subtask with processing of objects and tools in

SUBMITTER: Pupikova M 

PROVIDER: S-EPMC8328716 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature