Child reward neurocircuitry and parental substance use history: Findings from the Adolescent Brain Cognitive Development Study.

ABSTRACT:

Background

Substance use research has focused on family history of alcohol use disorders but less on other addictions in biological family members. We examined how parental substance use history relates to reward system functioning, specifically nucleus accumbens (NAcc) and putamen activation at age 9-10 in the Adolescent Brain Cognitive Development (ABCD) Study. This research hopes to address limitations in prior literature by focusing analyses on a large, substance-naïve sample.

Method

We included ABCD participants with valid Monetary Incentive Delay task fMRI Baseline data and parent substance use history at project baseline from Data Release 2.0 (N = 10,622). Parent-history-positive (PH+) participants had one or both biological parents with a history of two+problems with

SUBMITTER: Kwarteng AE 

PROVIDER: S-EPMC8328938 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature