Defining Multimorbidity and Its Impact in Older United States Veterans Newly Treated for Multiple Myeloma.

ABSTRACT:

Background

Traditional count-based measures of comorbidity are unlikely to capture the complexity of multiple chronic conditions (multimorbidity) in older adults with cancer. We aimed to define patterns of multimorbidity and their impact in older United States veterans with multiple myeloma (MM).

Methods

We measured 66 chronic conditions in 5076 veterans aged 65 years and older newly treated for MM in the national Veterans Affairs health-care system from 2004 to 2017. Latent class analysis was used to identify patterns of multimorbidity among these conditions. These patterns were then assessed for their association with overall survival, our primary outcome. Secondary outcomes included emergency department visits and hospitalizations.

Results

Five patterns of multimor

SUBMITTER: Fillmore NR 

PROVIDER: S-EPMC8328982 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature