Linking objective measures of physical activity and capability with brain structure in healthy community dwelling older adults.

ABSTRACT: Maintaining high levels of daily activity and physical capability have been proposed as important constituents to promote healthy brain and cognitive aging. Studies investigating the associations between brain health and physical activity in late life have, however, mainly been based on self-reported data or measures designed for clinical populations. In the current study, we examined cross-sectional associations between physical activity, recorded by an ankle-positioned accelerometer for seven days, physical capability (grip strength, postural control, and walking speed), and neuroimaging based surrogate markers of brain health in 122 healthy older adults aged 65-88 years. We used a multimodal brain imaging approach offering complementary structural MRI based indicators of brain health: g

SUBMITTER: Sanders AM 

PROVIDER: S-EPMC8329542 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature