The disrupted topological properties of structural networks showed recovery in ischemic stroke patients: a longitudinal design study.

ABSTRACT:

Introduction

Stroke is one of the leading causes of substantial disability worldwide. Previous studies have shown brain functional and structural alterations in adults with stroke. However, few studies have examined the longitudinal reorganization in whole-brain structural networks in stroke.

Methods

Here, we applied graph theoretical analysis to investigate the longitudinal topological organization of white matter networks in 20 ischemic stroke patients with a one-month interval between two timepoints. Two sets of clinical scores, Fugl-Meyer motor assessment (FMA) and neurological deficit scores (NDS), were assessed for all patients on the day the image data were collected.

Results

The stroke patients exhibited significant increases in FMA scores and significant redu

SUBMITTER: Li Y 

PROVIDER: S-EPMC8330082 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature