Prolonged viral shedding of SARS-CoV-2 in two immunocompromised patients, a case report.

ABSTRACT:

Background

The duration of viable Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) shedding in immunocompromised patients is still unknown. This case report describes the duration of viable SARS-CoV-2 in two immunocompromised patients with completely different clinical courses and further addresses the immunological aspects.

Case presentations

Oropharyngeal swaps were collected continuously during hospitalization for two immunocompromised patients infected with SARS-CoV-2 and sent for analysis to real time reverse transcription polymerase chain reaction (RT-PCR), viral culture assessed by plaque assay and full genome sequencing. Blood samples for flow cytometry and further immunological analysis were taken once during admission. One patient was without symptoms o

SUBMITTER: Niyonkuru M 

PROVIDER: S-EPMC8330202 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature