Rapid, early and accurate SARS-CoV-2 detection using RT-qPCR in primary care: a prospective cohort study (REAP-1).

ABSTRACT:

Objectives

We explore the importance of SARS-CoV-2 sentinel surveillance testing in primary care during a regional COVID-19 outbreak in Austria.

Design

Prospective cohort study.

Setting

A single sentinel practice serving 22 829 people in the ski-resort of Schladming-Dachstein.

Participants

All 73 patients presenting with mild-to-moderate flu-like symptoms between 24 February and 03 April, 2020.

Intervention

Nasopharyngeal sampling to detect SARS-CoV-2 using real-time reverse transcriptase-quantitative PCR (RT-qPCR).

Outcome measures

We compared RT-qPCR at presentation with confirmed antibody status. We split the outbreak in two parts, by halving the period from the first to the last case, to characterise three cohorts of patients with confirmed in

SUBMITTER: Leber W 

PROVIDER: S-EPMC8331320 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature