Antidiuretic hormone and the activation of glucose production during high intensity aerobic exercise.

ABSTRACT:

Objective

This study aimed to investigate the role that antidiuretic hormone (ADH) may play in the activation of glucose production during high intensity aerobic exercise.

Materials/methods

This study was part of larger study based on a repeated measures cross-over study design and involved ten adult participants who exercised in the morning at 80 % V̇O₂peak for up to 40 min or until exhaustion. During and after exercise, the participants were subjected to a morning euglycaemic/euinsulinaemic clamp while [6,6-²H₂]glucose was infused and blood sampled to measure the endogenous rate of glucose appearance (Ra) and ADH levels.

Results

The levels of plasma ADH were 1.8 ± 0.2 pmol/L (mean ± SEM) at rest and increased to 10.5 ± 2.1 pmo

SUBMITTER: Shetty VB 

PROVIDER: S-EPMC8333141 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature