Lurasidone in the long-term treatment of Japanese patients with bipolar I disorder: a 52 week open label study.

ABSTRACT:

Background

The current study evaluated the long-term (52 week) safety and impact on symptom measures of lurasidone (with or without lithium or valproate) for the treatment of bipolar I disorder in Japanese patients.

Methods

Bipolar patients for this open-label flexibly dosed lurasidone (20-120 mg/day) study were recruited from those with a recent/current depressive episode who completed an initial 6 week, double-blind, placebo-controlled, lurasidone study (depressed group), and those with a recent/current manic, hypomanic, or mixed episode (non-depressed group) who agreed to enroll directly into the long-term study. Measures of adverse events and safety included treatment-emergent adverse events, vital signs, body weight, ECG, laboratory tests, and measures of suicidality an

SUBMITTER: Higuchi T 

PROVIDER: S-EPMC8333182 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature