TrendyGenes, a computational pipeline for the detection of literature trends in academia and drug discovery.

ABSTRACT: Target identification and prioritisation are prominent first steps in modern drug discovery. Traditionally, individual scientists have used their expertise to manually interpret scientific literature and prioritise opportunities. However, increasing publication rates and the wider routine coverage of human genes by omic-scale research make it difficult to maintain meaningful overviews from which to identify promising new trends. Here we propose an automated yet flexible pipeline that identifies trends in the scientific corpus which align with the specific interests of a researcher and facilitate an initial prioritisation of opportunities. Using a procedure based on co-citation networks and machine learning, genes and diseases are first parsed from PubMed articles using a novel named entity

SUBMITTER: Serrano Najera G 

PROVIDER: S-EPMC8333311 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature