Feasibility of bone marrow mesenchymal stem cells harvesting from forearm bone.

ABSTRACT:

Introduction

Mesenchymal stem cell is a promising therapeutic option in orthopedic filed and regenerative medicine. The feasibility of isolation method and characterization of Mesenchymal stem cell including growth kinetics, immunophenotypes and differentiation potency from small volume aspiration harvested from ulna and radius should be evaluated in order to utilize this cell in hand surgery.

Materials and methods

Mesenchymal stem cells were isolated and characterized from bone marrow of 12 patients who underwent internal fixation of fractures at radius or ulna. Population doubling time & clonogenic ability, immunophenotypes and trilineage differentiation potential of Mesenchymal stem cells were evaluated.

Results

Mesenchymal stem cells derived from bone marrow were

SUBMITTER: Tawonsawatruk T 

PROVIDER: S-EPMC8334379 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature