Complete Genome Sequences of Two Novel KPC-2-Producing IncU Multidrug-Resistant Plasmids From International High-Risk Clones of Escherichia coli in China.

ABSTRACT: The rapidly increasing prevalence of Klebsiella pneumoniae carbapenemase 2 (KPC-2)-producing bacteria has become a serious challenge to public health. Currently, the bla _{KPC- 2} gene is mainly disseminated through plasmids of different sizes and replicon types. However, the plasmids carrying the bla _{KPC- 2} gene have not been fully characterized. In this study, we report the complete genome sequences of two novel bla _{KPC- 2}-harboring incompatibility group U (IncU) plasmids, pEC2341-KPC and pEC2547-KPC, from international high-risk clones of Escherichia coli isolated from Zhejiang, China. Two KPC-2-producing E. coli isolates (EC2341 and EC2547) were collected from c

SUBMITTER: Wu W 

PROVIDER: S-EPMC8335537 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature