Intra-fractional dosimetric analysis of image-guided intracavitary brachytherapy of cervical cancer.

ABSTRACT:

Background

To assess the intra-fractional dosimetric variations of image-guided brachytherapy of cervical cancer.

Methods

A total of 38 fractions (9 patients) undergoing brachytherapy for cervical cancer underwent a CT scanning for treatment planning (planning CT) and a Cone-beam CT (CBCT) scanning immediately prior to delivery (pre-delivery CBCT). The variations of volumes as well as the dosimetric impact from treatment planning to delivery (intra-application) were evaluated. The dose volume histogram parameters including volume, D90 of high-risk clinical target volume (HRCTV) and D2cc of organs at risk (OARs) were recorded.

Results

The relative differences (mean ± 1SD) of the volume and D90 HRCTV across the two scans were - 2.0 ± 3.3% and - 1.2 ± 4.5%, respectively.

SUBMITTER: Yan J 

PROVIDER: S-EPMC8335895 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature