Comparing two fluoride therapies for caries management in young children: study protocol for a randomised clinical trial.

ABSTRACT:

Background

Silver diamine fluoride (SDF) and sodium fluoride (NaF) are widely used for caries management. The objectives of this study are (i) to compare the caries-arresting and caries-preventive effects of SDF and NaF in young children, (ii) to determine children's and parents' acceptance of these fluoride therapies and (iii) to investigate the short-term (1 day) and long-term (1 year) adverse effects of these fluoride therapies.

Methods/design

This is a randomised, double-blind, active-controlled clinical trial to be conducted in Hong Kong kindergartens. The study has received approval from the local institutional review board. Written consent will be obtained from the parents/guardians before the study. The study will recruit at least 688 healthy 3-year-old children. Thi

SUBMITTER: Gao SS 

PROVIDER: S-EPMC8335970 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature