Network Approach to Source Attribution of Salmonella enterica Serovar Typhimurium and Its Monophasic Variant.

ABSTRACT: Salmonella enterica subspecies enterica serovar Typhimurium and its monophasic variant are among the most common Salmonella serovars associated with human salmonellosis each year. Related infections are often due to consumption of contaminated meat of pig, cattle, and poultry origin. In order to evaluate novel microbial subtyping methods for source attribution, an approach based on weighted networks was applied on 141 human and 210 food and animal isolates of pigs, broilers, layers, ducks, and cattle collected in Denmark from 2013 to 2014. A whole-genome SNP calling was performed along with cgMLST and wgMLST. Based on these genomic input data, pairwise distance matrices were built and used as input for construction of a weighted network where nodes represent genomes and links

SUBMITTER: Merlotti A 

PROVIDER: S-EPMC8335978 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature