Modeling of Quasi-Static Floating-Gate Transistor Biosensors.

ABSTRACT: Floating-gate transistors (FGTs) are a promising class of electronic sensing architectures that separate the transduction elements from molecular sensing components, but the factors leading to optimum device design are unknown. We developed a model, generalizable to many different semiconductor/dielectric materials and channel dimensions, to predict the sensor response to changes in capacitance and/or charge at the sensing surface upon target binding or other changes in surface chemistry. The model predictions were compared to experimental data obtained using a floating-gate (extended gate) electrochemical transistor, a variant of the generic FGT architecture that facilitates low-voltage operation and rapid, simple fabrication using printing. Self-assembled monolayer (SAM) chemistry and qu

SUBMITTER: Thomas MS 

PROVIDER: S-EPMC8336320 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature