Inflammatory metabolic profile of South African patients with prostate cancer.

ABSTRACT:

Background

Men with African ancestry are more likely to develop aggressive prostate cancer (PCa) and to die from this disease. The study of PCa in the South African population represents an opportunity for biomedical research due to the high prevalence of aggressive PCa. While inflammation is known to play a significant role in PCa progression, its association with tumor stage in populations of African descent has not been explored in detail. Identification of new metabolic biomarkers of inflammation may improve diagnosis of patients with aggressive PCa.

Methods

Plasma samples were profiled from 41 South African men with PCa using nuclear magnetic resonance (NMR) spectroscopy. A total of 41 features, including metabolites, lipid classes, total protein, and the inflammatory N

SUBMITTER: Cacciatore S 

PROVIDER: S-EPMC8336341 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature